Article

GDV1 C-terminal truncation of 39 amino acids disrupts sexual commitment in <i>Plasmodium falciparum</i>

2020-10-30

Abstract excerpt

Malaria is a mosquito-borne disease caused by apicomplexan parasites of the genus Plasmodium. Completion of the parasite’s life cycle depends on the transmission of sexual stages, the gametocytes, from an infected human host to the mosquito vector. Sexual commitment occurs in only a small fraction of asexual blood stage parasites and is initiated by external cues. The gametocyte development protein 1 (GDV1) has b...

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Literature Corpus work: 99a8fbe6-e6e0-5b80-9552-34169cf81dd9
DOI: 10.1101/2020.10.28.360123

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