Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research

10 Aug 2021

Abstract excerpt

The malaria parasite Plasmodium falciparum replicates inside erythrocytes in the blood of infected humans. During each replication cycle, a small proportion of parasites commits to sexual development and differentiates into gametocytes, which are essential for parasite transmission via the mosquito vector. Detailed molecular investigation of gametocyte biology and transmission has been hampered by difficulties in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Invertebrate Immune Response Mechanisms
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34376675
DOI: 10.1038/s41467-021-24954-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission researchPMID 34376675Read ↗

CRISPR/Cas9-engineered inducible gametocyte producer lines as a novel tool for basic and applied research on <i>Plasmodium falciparum</i> malaria transmission stagesSemantic proximity Read ↗

CRISPR/Cas9-engineered inducible gametocyte producer lines as a novel tool for basic and applied research on Plasmodium falciparum malaria transmission stagesSemantic proximity Read ↗

Targeting Gametocytes of the Malaria Parasite Plasmodium falciparum in a Functional Genomics Era: Next StepsSemantic proximity Read ↗

Plasmodium falciparum Development from Gametocyte to Oocyst: Insight from Functional StudiesSemantic proximity Read ↗

Sexual Development in Plasmodium: Lessons from Functional AnalysesSemantic proximity Read ↗

Experimental Genetics Validation of <i>Plasmodium falciparum</i> Gametogenesis Essential Protein 1 (GEP1) as a Transmission Blocking TargetSemantic proximity Read ↗

Phenotypic Screens Identify Genetic Factors Associated with Gametocyte Development in the Human Malaria Parasite Plasmodium falciparum.Semantic proximity Read ↗

Transgenic pyrimethamine-resistant plasmodium falciparum reveals transmission-blocking potency of P218, a novel antifolate candidate drug.Semantic proximity Read ↗

GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencingSemantic proximity Read ↗

A Conditional Cas9 System for Stage-Specific Gene Editing in <i>P. falciparum</i>Semantic proximity Read ↗

Large-Scale Mutagenesis Screening for Genetic Determinants of Plasmodium falciparum Sexual Development.Semantic proximity Read ↗

Transgenic pyrimethamine-resistant <i>P. falciparum</i> reveals transmission blocking potency of P218, a novel antifolateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.