Article

CRISPR/Cas9-engineered inducible gametocyte producer lines as a novel tool for basic and applied research on Plasmodium falciparum malaria transmission stages

2020-10-21

Abstract excerpt

<title>Abstract</title> The malaria parasite Plasmodium falciparum replicates inside erythrocytes in the blood of infected humans. During each replication cycle, a small proportion of parasites commits to sexual development and differentiates into gametocytes, which are essential for parasite transmission to other human hosts via the mosquito vector. Detailed molecular investigation of gametocyte biology and t...

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Literature Corpus work: a3bc3b6f-982c-5732-8b93-b8041de057f5
DOI: 10.21203/rs.3.rs-88204/v1

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