Article

Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons

2017-05-27

Abstract excerpt

Autism spectrum disorder (ASD) is highly heritable but genetically heterogeneous. The affected neural circuits and cell types remain unclear and may vary at different developmental stages. By analyzing multiple sets of human single cell transcriptome profiles, we found that ASD candidates showed enriched gene expression in neurons, especially in inhibitory neurons. ASD candidates were also more likely to be the hu...

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Literature Corpus work: 52320a8f-ade6-5793-8b1f-2ab8f7e34bb8
DOI: 10.1101/142968

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