Article
Genome-wide analysis of somatic non-coding mutation patterns and mitochondrial heteroplasmy in type B1 and B2 thymomas
2024-08-10
Abstract excerpt
<h4>Introduction</h4> Type B1 and B2 thymomas are lymphocyte-rich malignant tumors with few somatic mutations in protein-coding regions of the nuclear genome; nonetheless, non-coding regions remain uncharacterized. Here, we developed a rigorous tumor isolation method from lymphocyte-rich thymoma tissues and identified somatic mutations in non-coding and mitochondrial DNA. <h4>Methods</h4> CD205 + CD45 - pure t...
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Identifiers and source
- Literature Corpus work
- 7b9dbc0f-664c-5d92-916d-661247637117
- DOI
- 10.1101/2024.08.09.607250