Article

Characteristics of GTF2I L424H Mutated Thymoma and its Prognostic Impact: A Comprehensive Study

2024-09-26

Abstract excerpt

<title>Abstract</title> <p>Thymic Epithelial Tumor (TET), a rare thoracic tumor, including thymoma and thymic carcinoma, has limited research on thymoma prognostic markers compared to thymic carcinoma. Using the cBiportal database, we analyzed gene expression, methylation, and mutation data in TETs. We explored the relationship between the <italic>GTF2I</italic> L424H mutation and thymoma pathology through differ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4abf2121-862b-5062-8f3c-0f621cb2b0ad
DOI: 10.21203/rs.3.rs-4860772/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characteristics of GTF2I L424H Mutated Thymoma and its Prognostic Impact: A Comprehensive StudyDOI 10.21203/rs.3.rs-4860772/v1Read

The Molecular Landscape of Thymic Epithelial Tumors: A Comprehensive ReviewSemantic proximity Read

The Integrated Genomic Landscape of Thymic Epithelial Tumors.Semantic proximity Read

Characteristics of Genomic Mutations and Signaling Pathway Alterations in Thymic Epithelial TumorsSemantic proximity Read

Significance of tumor mutation burden and immune infiltration in thymic epithelial tumors.Semantic proximity Read

Integrative Multiomic Classification Reveals Distinct Origins and Evolutionary Trajectories of Thymic Epithelial Tumors.Semantic proximity Read

Integrated Molecular and Clinical Analysis of Thymic Epithelial Tumors.Semantic proximity Read

GTF2I mutation frequently occurs in more indolent thymic epithelial tumors and predicts better prognosis.Semantic proximity Read

Genetic alterations leading to thymic epithelial malignanciesSemantic proximity Read

Investigation of the prognostic biomarkers for thymomaSemantic proximity Read

Genomic characterization of thymic epithelial tumors in a real-world datasetSemantic proximity Read

Primary Driver Mutations in GTF2I Specific to the Development of ThymomasSemantic proximity Read

Prognostic analysis of tumor mutation burden combined with immune infiltration of Thymic epithelial tumorsSemantic proximity Read