Comparative Analysis of Comprehensive Genomic Profile in Thymomas and Recurrent Thymomas Reveals Potentially Actionable Mutations for Target Therapies.

doi:10.3390/ijms25179560

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Article

Comparative Analysis of Comprehensive Genomic Profile in Thymomas and Recurrent Thymomas Reveals Potentially Actionable Mutations for Target Therapies.

International journal of molecular sciences - 3 Sept 2024

Lococo Filippo, De Paolis Elisa, Evangelista Jessica, Dell'Amore Andrea, Giannarelli Diana, Chiappetta Marco, Campanella Annalisa, Sassorossi Carolina, Cancellieri Alessandra, Calabrese Fiorella, Conca Alessandra, Vita Emanuele, Minucci Angelo, Bria Emilio, Castello Angelo, Urbani Andrea, Rea Federico, Margaritora Stefano, Scambia Giovanni

Abstract excerpt

Molecular profiles of thymomas and recurrent thymomas are far from being defined. Herein, we report an analysis of a comprehensive genetic profile (CGP) in a highly selected cohort of recurrent thymomas. Among a cohort of 426 thymomas, the tissue was available in 23 recurrent tumors for matching the biomolecular results obtained from primary and relapse samples. A control group composed of non-recurrent thymoma...

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Identifiers

PMID: 39273507
DOI: 10.3390/ijms25179560
PMCID: PMC11394945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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