Constant p.L424H Mutation in GTF2I in Micronodular Thymomas With Lymphoid Stroma: Evidence Supporting Close Relationship With Type A and AB Thymomas.

doi:10.1016/j.modpat.2022.100008

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Constant p.L424H Mutation in GTF2I in Micronodular Thymomas With Lymphoid Stroma: Evidence Supporting Close Relationship With Type A and AB Thymomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2023

Hsieh Min-Shu, Kao Hua-Lin, Huang Wen-Chang, Wang Shu-Ying, Lin Shin-Ying, Chu Ping-Yuan, Pan Chin-Chen, Chou Teh-Ying, Ho Hsiang-Ling, Yeh Yi-Chen

Abstract excerpt

Micronodular thymoma with lymphoid stroma is a rare thymic neoplasm characterized by discrete nodules of epithelial tumor cells separated by abundant lymphoid stroma. The genetic features of micronodular thymoma with lymphoid stroma remain largely unexplored. Owing to the interference of abundant intratumoral, nonneoplastic lymphoid cells, a highly sensitive approach is necessary to study genetic changes in these...

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Constant p.L424H Mutation in GTF2I in Micronodular Thymomas With Lymphoid Stroma: Evidence Supporting Close Relationship With Type A and AB Thymomas.

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