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Article

Integrated Molecular and Clinical Analysis of Thymic Epithelial Tumors.

JCO precision oncology - 1 Jun 2026

Kim Chul, Adeyelu Tolulope, Maniar Rohan, Farrell Alex, Zaemes Jacob, Solzak Jeffrey, Hancock Bradley, Elliott Andrew, Micaily Ida, Nagasaka Misako, Nieva Jorge, Borghaei Hossein, Halmos Balazs, Ma Patrick C, Radovich Milan, Badve Sunil S, Loehrer Patrick J

Abstract excerpt

PURPOSE: Thymic epithelial tumors (TETs), which include thymomas and thymic carcinomas (TCs), are the most common neoplasms of the anterior mediastinum. To develop more effective therapeutics, it is necessary to better understand their molecular characteristics. METHODS: TET samples were profiled using next-generation sequencing (NGS) of DNA (592-gene panel or whole-exome sequencing) and RNA (whole-transcriptome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42258781
DOI: 10.1200/PO-26-00001

Genes

CDKN2A
TP53
CDKN2B
EGFR
ERBB2
ERBB3
KIT
MSLN
MTAP
MYC
NECTIN4
TACSTD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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