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Article

Integrative Multiomic Classification Reveals Distinct Origins and Evolutionary Trajectories of Thymic Epithelial Tumors.

Cancer research - 16 Mar 2026

Park Seongyeol, Yi Kijong, Lee Jieun, Yang Myung Jin, Song Joo-Hye, Lim Joonoh, Kim Taewoo, Kim Seokhwi, Kim Su Yeon, Kim Hyung-Don, Kim Yoon Ho, Lee Sae Bom, Jung Yoo Jin, Park Hansol, Lee Jake June-Koo, An Yohan, Youk Jeonghwan, Na Kwon Joong, Park Samina, Lee Hyun Joo, Park In Kyu, Kang Chang Hyun, Shin Eui-Cheol, Kim Tae Min, Heo Won Do, Lee Charles, Koh Gou Young, Cho Sung-Yup, Ju Young Seok, Kim Young Tae

Abstract excerpt

Thymic epithelial tumors (TET), comprising various histologic types of thymomas and thymic carcinomas, originate from thymic epithelial cells (TEC). Each histologic type is typically associated with a distinct immune cell composition and clinical manifestation. A better understanding of the cellular origins and molecular pathways underlying this heterogeneity is needed to improve patient stratification and...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Glandular and Epithelial

Share to Single-Cell Gene Expression Analysis

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Share to Transcription Factors, TFII

Source

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Identifiers

PMID: 41671387
DOI: 10.1158/0008-5472.CAN-24-4977
PMCID: PMC13012242

Genes

GTF2I
IRS4
TEC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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