Article

Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics

2022-10-02

Abstract excerpt

While advances in single cell genomics have helped to chart the cellular components of tumor ecosystems, it has been more challenging to characterize their specific spatial organization and functional interactions. Here, we combine single cell RNA-seq, spatial transcriptomics by Slide-seq, and in situ multiplex RNA analysis, to create a detailed spatial map of healthy and dysplastic colon cellular ecosystems and...

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Literature Corpus work: 7b9a6df6-a8e5-5a4f-9102-393fd449bcee
DOI: 10.1101/2022.10.02.508492

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