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Article

High-resolution integrative analysis allows characterization and spatial annotation of normal and cancer-associated colon fibroblasts

2025-07-31

Abstract excerpt

<h4>ABSTRACT</h4> Fibroblasts represent key regulators of colon homeostasis, and cancer-associated fibroblasts (CAFs) play pivotal roles in colorectal cancer (CRC). Despite their critical influence, a consensus view of adult human colon fibroblast and CRC CAF heterogeneity, spatial organization, and developmental trajectories is currently lacking. Here, we address this gap by performing a comprehensive characteri...

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Literature Corpus work
be72a073-a8e7-5c85-81a7-fc1c67cfb99a
DOI
10.1101/2025.07.29.667377
Open publication

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High-resolution integrative analysis allows characterization and spatial annotation of normal and cancer-associated colon fibroblastsDOI 10.1101/2025.07.29.667377
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