Article

Higher rates of processed pseudogene acquisition in humans and three great apes revealed by long read assemblies

2020-06-08

Abstract excerpt

LINE-1 mediated retrotransposition of protein-coding mRNAs is an active process in modern humans for both germline and somatic genomes. Prior works that surveyed human data or human cohorts mostly relied on detecting discordant mappings of paired-end short reads, or assumed L1 hallmarks such as polyA tails and target site duplications. Moreover, there has been few genome-wide comparison between gene retrocopies in...

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Literature Corpus work: 7b796bde-eaa3-5a5c-b033-78bc2661e1c5
DOI: 10.1101/2020.06.07.139212

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