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Article

Whole-genome screening indicates a possible burst of formation of processed pseudogenes and Alu repeats by particular L1 subfamilies in ancestral primates.

Genome biology - 1 Jan 2003

Ohshima Kazuhiko, Hattori Masahira, Yada Tetsusi, Gojobori Takashi, Sakaki Yoshiyuki, Okada Norihiro

Abstract excerpt

BACKGROUND: Abundant pseudogenes are a feature of mammalian genomes. Processed pseudogenes (PPs) are reverse transcribed from mRNAs. Recent molecular biological studies show that mammalian long interspersed element 1 (L1)-encoded proteins may have been involved in PP reverse transcription. Here, we present the first comprehensive analysis of human PPs using all known human genes as queries. RESULTS: The human...

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Identifiers

PMID: 14611660
DOI: 10.1186/gb-2003-4-11-r74
PMCID: PMC329124

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