Article
Using pseudogene database to identify lineage-specific genes and pseudogenes in humans and chimpanzees.
The Journal of heredity - 1 Jan 2000
Zhang Qu
Abstract excerpt
It has been revealed that gene content changes, or gene gains or losses, have played an important role in the evolution of modern humans. As one of the major players accounting for gene content changes, gene pseudogenization is abundant in mammalian genomes, and approximately 20000 pseudogenes have been identified in ape genomes. Therefore, it is an interesting question how to exploit rich information embedded in...
Read the complete abstract on PubMedTopics
- Animals
- Base Sequence
- Biological Evolution
- Computational Biology
- Databases, Genetic
- Evolution, Molecular
- Gene Expression Profiling