Article

Formation of human long intergenic non-coding RNA genes and pseudogenes: ancestral sequences are key players

2019-10-31

Abstract excerpt

Pathways leading to formation of non-coding RNA and protein genes are varied and complex. We report finding a highly conserved repeat sequence present in both human and chimpanzee genomes that appears to have originated from a common primate ancestor. This sequence is repeatedly copied in human chromosome 22 (chr22) low copy repeats (LCR22) or segmental duplications and forms twenty-one different genes, which incl...

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Literature Corpus work: e0d8a7db-7d63-5525-951c-26e4275f8e12
DOI: 10.1101/826784

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