Article

Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

2021-03-30

Abstract excerpt

Pseudogenes are gene copies presumed to mainly be functionless relics of evolution due to acquired deleterious mutations or transcriptional silencing. When transcribed, pseudogenes may encode proteins or enact RNA-intrinsic regulatory mechanisms. However, the extent, characteristics and functional relevance of the human pseudogene transcriptome are unclear. Short-read sequencing platforms have limited power to res...

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Literature Corpus work: 10b415fe-7750-5e77-aec8-07c4e1ed10e4
DOI: 10.1101/2021.03.29.437610

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