Article

Fast Surface Immobilization of Native Proteins through Metal-Free Amino-yne Click Bioconjugation

2019-11-25

Abstract excerpt

In this work, we use a spontaneous and catalyst-free amino-yne click bioconjugation to generate activated ethynyl group functionalized surfaces for fast immobilizing native proteins and cells. Biomolecules, such as bovine serum albumin (BSA), human IgG and peptide of C(RGDfK), could be covalently immobilized on the surfaces in as short as 30 min. Notably, the bioactivity of the anchored biomolecules remain in...

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Literature Corpus work: 7b643243-6a16-51ad-8648-2e063b6b1ae2
DOI: 10.26434/chemrxiv.10303412.v1

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