Article

Ultrafast tyrosine-based cell membrane modification <i>via</i> diazonium salts: a new frontier for biomedical applications

2025-11-16

Abstract excerpt

In this study, we present an ultrafast, efficient, and broadly applicable strategy for cell membrane modification via tyrosine bioconjugation using diazonium salt derivatives. This chemical approach enables both one-step and two-step functionalization of adherent, suspension, and primary cells with diverse ligands, including imaging probes, carbohydrates, biotin, and proteins, without inducing cytotoxicity or imm...

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Literature Corpus work: 4f099199-71d5-545d-80d5-265bb8be9f3b
DOI: 10.1101/2025.11.15.688583

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