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Protein‐Templated Reactions Using DNA‐Antibody Conjugates

28 Mar 2022

Abstract excerpt

DNA-templated chemical reactions have found wide applications in drug discovery, programmed multistep synthesis, nucleic acid detection, and targeted drug delivery. The control of these reactions has, however, been limited to nucleic acid hybridization as a means to direct the proximity between reactants. In this work a system capable of translating protein-protein binding events into a DNA-templated reaction...

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PMID: 35344264
DOI: 10.1002/smll.202200971

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