Article
Functionalization of lipid nanoemulsions with humanized antibodies using plug-and-play cholesterol anchor for targeting cancer cells
2025-07-04
Abstract excerpt
Lipid NEs are promising green nanocarriers for diagnostic and therapeutic applications, but their functionalization with biomolecules, such as antibodies, remains a challenge due to liquid nature of their core. Here, we developed an original plug-and-play strategy to graft an antibody (trastuzumab) at the surface of NEs, using components generally recognized as safe (GRAS). We synthesized a reactive derivative of...
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Identifiers and source
- Literature Corpus work
- 0db949b2-84bf-5027-8bcf-45df25b1a213
- DOI
- 10.1101/2025.06.29.662210