Article
An evidence-based approach to globally assess the covariate-dependent effect of MTHFR SNP rs1801133 on plasma homocysteine: a systematic review and meta-analysis
2017-10-17
Abstract excerpt
<h4>Background</h4> The single nucleotide polymorphism (SNP) of the gene Methylenetetrahydrofolate Reductase (MTHFR) C677T (or rs1801133) is the most established genetic factor that increases plasma total homocysteine (tHcy) and consequently results in hyperhomocysteinemia. Yet given the limited penetrance of this genetic variant, it is necessary to individually predict the risk of hyperhomocysteinemia for a rs18...
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Identifiers and source
- Literature Corpus work
- 7b590aa6-942e-54fa-a6fa-f3ca0698d636
- DOI
- 10.1101/204487