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Article

Quantitative assessment of association between rs1801133 polymorphism and susceptibility to stroke.

Cell biochemistry and biophysics - 1 Jan 2015

Zhang Wei, Wang Ye, Bi Guorong

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme involved in folate metabolism, which is essential for DNA synthesis and methylation. Genetic variations in the MTHFR gene seem to contribute to a decreased activity of MTHFR, ultimately confer increased susceptibility to stroke. To assess the association between this polymorphism and stroke risk, we conducted a comprehensive meta-analysis based on...

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Share to MTHFR gene
Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 25107455
DOI: 10.1007/s12013-014-0166-3

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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