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Methylenetetrahydrofolate Reductase Polymorphism (rs1801133) and the Risk of Hypertension among African Populations: A Narrative Synthesis of Literature.

Genes - 1 Apr 2022

Mabhida Sihle E, Muhamed Babu, Sharma Jyoti R, Apalata Teke, Nomatshila Sibusiso, Mabasa Lawrence, Benjeddou Mongi, Masilela Charity, Ziqubu Khanyisani, Shabalala Samukelisiwe, Johnson Rabia

Abstract excerpt

In this review, we have gathered and analyzed the available genetic evidence on the association between the methylenetetrahydrofolate reductase gene (MTHFR), rs1801133 and the risk of Hypertension (HTN) in African populations, which was further compared to the global data evidence. This review was reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol and Human...

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PMID: 35456437
DOI: 10.3390/genes13040631
PMCID: PMC9027465

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