Article

Decoding Immune Reconstitution Failure in People Living with HIV through Single-cell Genomics

2026-05-23

Abstract excerpt

Immune non-responders (INRs), a subset of people living with HIV (PLWH), fail to achieve full immune reconstitution and remain at increased risk of morbidity, mortality, and non-AIDS-related illnesses. As the mechanisms underlying this impaired immune recovery remain poorly understood, we performed single-cell multi-omics profiling on peripheral blood mononuclear cells from 43 INRs, 47 immune responders and 53 hea...

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Literature Corpus work: 7b4f3d63-934a-5a6d-b93c-58c88047916e
DOI: 10.64898/2026.05.21.726797

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