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Global transcriptomic characterization of T cells in individuals with chronic HIV-1 infection

28 Mar 2022

Abstract excerpt

Abstract To obtain a comprehensive scenario of T cell profiles and synergistic immune responses, we performed single-cell RNA sequencing (scRNA-seq) on the peripheral T cells of 14 individuals with chronic human immunodeficiency virus 1 (HIV-1) infection, including nine treatment-naive (TP) and eight antiretroviral therapy (ART) participants (of whom three were paired with TP cases), and compared the results with...

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PMID: 35351857
DOI: 10.1038/s41421-021-00367-x

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