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Article

Wip1 phosphatase: between p53 and MAPK kinases pathways.

Oncotarget - 24 May 2016

Goloudina Anastasia R, Kochetkova Elena Y, Pospelova Tatyana V, Demidov Oleg N

Abstract excerpt

Cells undergoing oncogenic transformation frequently inactivate tumor suppressor pathways that could prevent their uncontrolled growth. Among those pathways p53 and p38MAPK pathways play a critical role in regulation of cell cycle, senescence and cell death in response to activation of oncogenes, stress and DNA damage. Consequently, these two pathways are important in determining the sensitivity of tumor cells to...

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Share to Cell Cycle
Share to Cell Transformation, Neoplastic
Share to DNA Damage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to p38 Mitogen-Activated Protein Kinases

Share to Protein Phosphatase 2C

Share to Signal Transduction

Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 26883196
DOI: 10.18632/oncotarget.7325
PMCID: PMC5058778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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