Article

Knockout studies using CD34+ hematopoietic cells suggest that CD44 is a physiological human neutrophil E-selectin ligand

2023-08-19

Abstract excerpt

<h4>ABSTRACT</h4> The recruitment of peripheral blood neutrophils at sites of inflammation involves a multistep cascade, starting with E- and P-selectin expressed on the inflamed vascular endothelium binding sialofucosylated glycans on leukocytes. As the glycoconjugate biosynthesis pathways in different cells are distinct, the precise carbohydrate ligands of selectins varies both across species, and between diffe...

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Literature Corpus work: 7ab3d863-84d6-51f1-ab52-a334775e44bb
DOI: 10.1101/2023.08.18.553923

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