Article
Functions of selectins.
Results and problems in cell differentiation - 1 Jan 2001
Ley K
Abstract excerpt
The selectins are cell surface lectins that have evolved to mediate the adhesion of white blood cells to endothelial cells and platelets under flow. They recognize fucosylated, sialylated and in some cases sulfated ligands expressed on scaffold glycoproteins serving as functional counter-receptors. Selectins are regulated at the transcriptional level, through proteolytic processing, through cellular sorting, and...
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