Article

Influence of different glycoproteins and of the virion core on SERINC5 antiviral activity

2019-09-24

Abstract excerpt

<h4>ABSTRACT</h4> Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells. Three accessory proteins encoded by diverse retroviruses, HIV-1 Nef, EIAV S2, and MLV Glycogag, each independently disrupt SERINC5 antiviral activity, by redirecting SERINC5 from the site of virion assembly on the plasma membrane to an internal RA...

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Literature Corpus work: 7a40da93-5cfc-5b1f-8425-a856ccea4903
DOI: 10.1101/780577

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