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Article

Restriction of Influenza A Virus by SERINC5

21 Nov 2022

Abstract excerpt

SERINC5 (Ser5) is a cellular protein which has been found to interfere with the infectivity of HIV-1 and a number of other retroviruses. Virus particles produced in the presence of Ser5 are impaired in their ability to enter new host cells, but the mechanism of Ser5 action is not well understood. We now report that Ser5 also inhibits infectivity of Influenza A virus (IAV) and that it interferes with the...

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Identifiers

PMID: 36409124
DOI: 10.1128/mbio.02923-22

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