Article

Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription

2024-08-15

Abstract excerpt

Herpesviruses are ubiquitous pathogens that cause a wide range of disease. Upon nuclear entry, their genomes associate with histones and chromatin modifying enzymes that regulate the progression of viral transcription and outcome of infection. While the composition and modification of viral chromatin has been extensively studied on bulk populations of infected cells by chromatin immunoprecipitation, this key regul...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7a3f1a36-2af4-5274-bd36-2692b224011e
DOI: 10.1101/2024.08.15.608064

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcriptionDOI 10.1101/2024.08.15.608064Read

Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcriptionSemantic proximity Read

Promyelocytic leukemia (PML) nuclear bodies (NBs) induce latent/quiescent HSV-1 genomes chromatinization through a PML NB/Histone H3.3/H3.3 Chaperone AxisSemantic proximity Read

Histone H2A variant H2A.B is enriched in transcriptionally active and replicating HSV-1 lytic chromatin.Semantic proximity Read

ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infectionSemantic proximity Read

Temporal Viral Genome-Protein Interactions Define Distinct Stages of Productive Herpesviral InfectionSemantic proximity Read

Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblastsSemantic proximity Read

Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblastsSemantic proximity Read

The HUSH epigenetic repressor complex silences PML nuclear body-associated HSV-1 quiescent genomesSemantic proximity Read

The HUSH epigenetic repressor complex silences PML nuclear bodies-associated HSV-1 quiescent genomesSemantic proximity Read

Role of ND10 nuclear bodies in the chromatin repression of HSV-1Semantic proximity Read

Herpes simplex virus type 1 reshapes host chromatin architecture via transcription machinery hijackingSemantic proximity Read

The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infectionSemantic proximity Read