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Dissecting the role of Amerindian genetic ancestry and <i>ApoE</i> ε4 allele on Alzheimer disease in an admixed Peruvian population

2020-03-11

Abstract excerpt

Alzheimer disease (AD) is the leading cause of dementia in the elderly and occurs in all ethnic and racial groups. ApoE ε4 is the most significant genetic risk factor for late-onset AD and shows the strongest effect among East Asian populations followed by non-Hispanic White populations and has a relatively lower effect in African descent populations. Admixture analysis in the African American and Puerto Rican po...

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Literature Corpus work
79fce900-a643-52f0-80e2-419bb4911410
DOI
10.1101/2020.03.10.985846
Open publication

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Dissecting the role of Amerindian genetic ancestry and <i>ApoE</i> ε4 allele on Alzheimer disease in an admixed Peruvian populationDOI 10.1101/2020.03.10.985846
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