Article

A genome-wide association study in Peruvians suggests new risk loci for Alzheimer Disease

2023-11-29

Abstract excerpt

Increasing ethnic/ancestral diversity in genetic studies is critical for defining the genetic architecture of Alzheimer disease (AD). Amerindian (AI) populations are substantially underrepresented in AD genetic studies. The Peruvian population, with up to ∼80% of AI ancestry, provides a unique opportunity to assess the role of AI ancestry in AD. We aimed to conduct a genome-wide association study and comprehensive...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7b64f7a0-e5da-5dad-b120-0363ef425f4b
DOI: 10.1101/2023.11.29.23299201

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A genome-wide association study in Peruvians suggests new risk loci for Alzheimer DiseaseDOI 10.1101/2023.11.29.23299201Read

Genetic Contributions to Alzheimer’s Disease and Frontotemporal Dementia in Admixed Latin American PopulationsSemantic proximity Read

Genome-wide association meta-analysis of Alzheimer's disease in Colombian, Argentinian, and Chilean populationsSemantic proximity Read

Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population.Semantic proximity Read

Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American PopulationsSemantic proximity Read

Dissecting the role of Amerindian genetic ancestry and <i>ApoE</i> ε4 allele on Alzheimer disease in an admixed Peruvian populationSemantic proximity Read

First GWAS on Alzheimer’s Disease in Argentina and Chile populationsSemantic proximity Read

Multi-ancestry meta-analysis and fine-mapping in Alzheimer’s DiseaseSemantic proximity Read

Identification of 16 novel Alzheimer’s disease susceptibility loci using multi-ancestry meta-analyses of clinical Alzheimer’s disease and AD-by-proxy cases from four whole genome sequencing datasetsSemantic proximity Read

Extended genome-wide association study employing the African Genome Resources Panel identifies novel susceptibility loci for Alzheimer’s Disease in individuals of African ancestrySemantic proximity Read

Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses.Semantic proximity Read

The first genome-wide association study in the Argentinian and Chilean populations identifies shared genetics with Europeans in Alzheimer's disease.Semantic proximity Read

Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.Semantic proximity Read