Article

Genome-wide association meta-analysis of Alzheimer's disease in Colombian, Argentinian, and Chilean populations

2026-04-08

Abstract excerpt

<title>Abstract</title> <p> Latin American populations are underrepresented in Alzheimer’s disease (AD) genome-wide association studies (GWAS), limiting ancestry-specific risk prediction. To address this gap, a GWAS was conducted with 254 AD cases and 241 controls from Colombia, followed by a trans-ancestry meta-analysis that incorporated cohorts from Colombia, Chile, Argentina, and the European EADB consortium....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3bd728b9-2b2b-5107-adf8-249b3fdd0db9
DOI: 10.21203/rs.3.rs-8996305/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association meta-analysis of Alzheimer's disease in Colombian, Argentinian, and Chilean populationsDOI 10.21203/rs.3.rs-8996305/v1Read

First GWAS on Alzheimer’s Disease in Argentina and Chile populationsSemantic proximity Read

The first genome-wide association study in the Argentinian and Chilean populations identifies shared genetics with Europeans in Alzheimer's disease.Semantic proximity Read

Multi-ancestry meta-analysis and fine-mapping in Alzheimer’s DiseaseSemantic proximity Read

Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease.Semantic proximity Read

Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American PopulationsSemantic proximity Read

Genetic Contributions to Alzheimer’s Disease and Frontotemporal Dementia in Admixed Latin American PopulationsSemantic proximity Read

Descriptive Analysis of Genetic Variants in Individuals Without a Clinical Diagnosis of Alzheimer’s Disease in a Population from Southwestern ColombiaSemantic proximity Read

A genome-wide association study in Peruvians suggests new risk loci for Alzheimer DiseaseSemantic proximity Read

A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects.Semantic proximity Read

Genomic analyses reveal new insights into Alzheimer's diseaseSemantic proximity Read

Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses.Semantic proximity Read

Identifying Individuals at High Risk for Alzheimer’s Disease Among Hispanics Using Single and Multi-Ancestry Polygenic Risk ScoresSemantic proximity Read