Article

Lmx1a drives Cux2 expression in the cortical hem through activation of a conserved intronic enhancer

2018-07-13

Abstract excerpt

During neocortical development, neurons are produced by a diverse pool of neural progenitors. A subset of progenitors express the Cux2 gene and are fate-restricted to produce certain neuronal subtypes, but the upstream pathways that specify these progenitor fates remain unknown. To uncover the transcriptional networks that regulate Cux2 expression in the forebrain, we characterized a conserved Cux2 enhancer tha...

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Literature Corpus work: 79ced1bb-d540-5015-90e0-1017c6276525
DOI: 10.1101/368555

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