Article
LIM-homeodomain gene Lhx2 regulates the formation of the cortical hem.
Mechanisms of development - 1 Feb 2001
Bulchand S, Grove E A, Porter F D, Tole S
Abstract excerpt
We are interested in the early mechanisms that initiate regional patterning in the dorsal telencephalon, which gives rise to cerebral cortex. Members of the LIM-homeodomain (LIM-HD) family of transcription factors are implicated in patterning and cell fate specification in several systems including the mammalian forebrain. Mice in which Lhx2 is disrupted were reported to have reduced telencephalic development,...
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