Article

Frequent <i>PIK3CA</i> mutations in eutopic endometrium of patients with ovarian clear cell carcinoma

2021-02-25

Abstract excerpt

Recent studies have reported cancer-associated mutations in normal endometrium. Mutations in eutopic endometrium may lead to endometriosis and endometriosis-associated ovarian cancer. We investigated PIK3CA mutations ( PIK3CA m) for three hotspots (E542K, E545K, H1047R) in eutopic endometrium in patients with ovarian cancer and endometriosis from formalin-fixed paraffin-embedded specimens by laser-capture microd...

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Literature Corpus work: 79bc2059-c380-50f5-b913-9af16be3fce6
DOI: 10.1101/2021.02.25.432943

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