Article
Molecular alterations of PIK3CA in uterine carcinosarcoma, clear cell, and serous tumors.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Sept 2014
Bashir Shazia, Jiang Gaofeng, Joshi Ayesha, Miller Christopher, Matrai Cathleen, Yemelyanova Anna, Caputo Thomas A, Holcomb Kevin M, Ellenson Lora Hedrick, Gupta Divya
Abstract excerpt
OBJECTIVES: Type II endometrial carcinomas-uterine carcinosarcomas or uterine malignant mesodermal mixed tumors (UMMMTs), clear cell carcinomas (UCCs), and uterine serous carcinomas (USCs)-are aggressive malignancies that present with advanced disease and have high mortality rates. PIK3CA mutations are commonly found in endometrial cancers. The objective of the study was to characterize molecular alterations in...
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