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Multiplexing Engineered Receptors for Multiparametric Evaluation of Environmental Ligands

3 Aug 2017

Abstract excerpt

Engineered cell-based therapies comprise a promising, emerging biomedical technology. Broad utilization of this strategy will require new approaches for implementing sophisticated functional programs, such as sensing and responding to the environment in a defined fashion. Toward this goal, we investigated whether our self-contained receptor and signal transduction system (MESA) could be multiplexed to evaluate...

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PMID: 28771312
DOI: 10.1021/acssynbio.6b00279

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