Article

Rapid evolution of piRNA clusters in the <i>Drosophila melanogaster</i> ovary

2023-05-10

Abstract excerpt

Animal genomes are parasitized by a horde of transposable elements (TEs) whose mutagenic activity can have catastrophic consequences. The piRNA pathway is a conserved mechanism to repress TE activity in the germline via a specialized class of small RNAs associated with effector Piwi proteins called piwi-associated RNAs (piRNAs). piRNAs are produced from discrete genomic regions called piRNA clusters (piCs). While...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 60a4718e-9799-5e13-9cee-3a537712936e
DOI: 10.1101/2023.05.08.539910

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rapid evolution of piRNA clusters in the <i>Drosophila melanogaster</i> ovaryDOI 10.1101/2023.05.08.539910Read

Rapid evolution of piRNA-mediated silencing of an invading transposable element was driven by abundant de novo mutations.Semantic proximity Read

Rapid evolutionary diversification of the <i>flamenco</i> locus across simulans clade <i>Drosophila</i> speciesSemantic proximity Read

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the <i>Drosophila</i> genusSemantic proximity Read

The Drosophila OSC Genome: A Resource for Studies of Transposon and piRNA BiologySemantic proximity Read

piRNA loss unleashes episodic transposition burstsSemantic proximity Read

Unique transposon landscapes are pervasive across Drosophila melanogaster genomes.Semantic proximity Read

<i>Flamenco</i> plasticity tunes somatic piRNAs, rewiring host isoforms and opening a route to heritable transposon spreadSemantic proximity Read

Functional Adaptations of Endogenous Retroviruses to the <i>Drosophila</i> Host Underlie their Evolutionary DiversificationSemantic proximity Read

Recurrent Gene Duplication Diversifies Genome Defense Repertoire in Drosophila.Semantic proximity Read

piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in <i>D. melanogaster</i> male germlineSemantic proximity Read

Population-scale long-read sequencing uncovers transposable elements contributing to gene expression variation and associated with adaptive signatures in <i>Drosophila melanogaster</i>Semantic proximity Read

Mechanistic divergence of piRNA biogenesis in DrosophilaSemantic proximity Read