Article
Spatio-temporal requirements for transposable element piRNA-mediated silencing during Drosophila oogenesis.
Nucleic acids research - 1 Feb 2014
Dufourt Jérémy, Dennis Cynthia, Boivin Antoine, Gueguen Nathalie, Théron Emmanuelle, Goriaux Coline, Pouchin Pierre, Ronsseray Stéphane, Brasset Emilie, Vaury Chantal
Abstract excerpt
During Drosophila oogenesis, transposable element (TE) repression involves the Piwi-interacting RNA (piRNA) pathway which ensures genome integrity for the next generation. We developed a transgenic model to study repression of the Idefix retrotransposon in the germline. Using a candidate gene KD-...
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