Article

<i>Har-P, a</i> short <i>P</i> -element variant, weaponizes <i>P</i> -transposase to severely impair <i>Drosophila</i> development

2019-07-11

Abstract excerpt

<h4>ABSTRACT</h4> Without transposon-silencing Piwi-interacting RNAs (piRNAs), transposition causes an ovarian atrophy syndrome in Drosophila called gonadal dysgenesis (GD). Harwich ( Har ) strains with P -elements cause severe GD in F1 daughters when Har fathers mate with mothers lacking P -element-piRNAs (i.e. ISO1 strain). To address the mystery of why Har induces severe GD, we bred hybrid Drosophila...

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Literature Corpus work: f2178f14-74d9-50ed-94c4-7c9a18e7920c
DOI: 10.1101/700211

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