Article

Multi-omics analysis of long-term cultured human islets

2024-12-25

Abstract excerpt

β-cell dysfunction in pancreatic islets, characterized as either the loss of β-cell mass or the resistance of β-cell to glucose, is the leading cause of progression to diabetes. Islet transplantation became a promising approach to replenish functional β-cell mass. However, not much known about changes in islets used for transplantation after isolation. We have subjected human islets into long-term in vitro cultur...

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Literature Corpus work: 7984a8bf-96fc-5c17-8bed-cfc7fa7e6950
DOI: 10.1101/2024.12.25.626491

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