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Pancreatic β-cell failure, clinical implications, and therapeutic strategies in type 2 diabetes

13 Mar 2024

Abstract excerpt

ABSTRACT: Pancreatic β-cell failure due to a reduction in function and mass has been defined as a primary contributor to the progression of type 2 diabetes (T2D). Reserving insulin-producing β-cells and hence restoring insulin production are gaining attention in translational diabetes research, and β-cell replenishment has been the main focus for diabetes treatment. Significant findings in β-cell proliferation,...

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PMID: 38479993
DOI: 10.1097/cm9.0000000000003034

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