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A transcriptional cross species map of pancreatic islet cells

13 Sept 2022

Abstract excerpt

OBJECTIVE: Pancreatic islets of Langerhans secrete hormones to regulate systemic glucose levels. Emerging evidence suggests that islet cells are functionally heterogeneous to allow a fine-tuned and efficient endocrine response to physiological changes. A precise description of the molecular basis of this heterogeneity, in particular linking animal models to human islets, is an important step towards identifying...

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PMID: 36113773
DOI: 10.1016/j.molmet.2022.101595

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