Article
Endocrine Pancreas Development and Dysfunction Through the Lens of Single-Cell RNA-Sequencing
29 Apr 2021
Abstract excerpt
A chronic inability to maintain blood glucose homeostasis leads to diabetes, which can damage multiple organs. The pancreatic islets regulate blood glucose levels through the coordinated action of islet cell-secreted hormones, with the insulin released by β-cells playing a crucial role in this process. Diabetes is caused by insufficient insulin secretion due to β-cell loss, or a pancreatic dysfunction. The...
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