Article

Functional dissection of metabolic trait-associated gene regulation in steady state and stimulated human skeletal muscle cells

2024-12-03

Abstract excerpt

Type 2 diabetes (T2D) is a common metabolic disorder characterized by dysregulation of glucose metabolism. Genome-wide association studies have defined hundreds of signals associated with T2D and related metabolic traits, predominantly in noncoding regions. While pancreatic islets have been a focal point given their central role in insulin production and glucose homeostasis, other metabolic tissues, including live...

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Literature Corpus work: 7978c53a-19d6-5fbb-95de-3593a0a96cce
DOI: 10.1101/2024.11.28.625886

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