Article

HELZ2: a new, interferon-regulated, human 3’-5’ exoribonuclease of the RNB family is expressed from a non-canonical initiation codon

2023-02-22

Abstract excerpt

Proteins containing a RNB domain, originally identified in E. coli RNase II, are widely present throughout the tree of life. Many RNB proteins are endowed with 3’-5’ exoribonucleolytic activity but some have lost catalytic function during evolution. Database searches identified a new RNB domain containing protein in human: HELZ2. Analysis of genomic and expression data with evolutionary information suggested that...

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Identifiers and source

Literature Corpus work: 7924fd4f-22ce-5423-b458-e5343e9840ee
DOI: 10.1101/2023.02.22.529493

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