Article

Bacterial and human exonucleases mediate interkingdom antiviral immunity

2026-07-01

Abstract excerpt

All kingdoms of life have developed strategies to limit viral infection 1,2 . In humans, interferons induce a suite of antiviral factors that collectively provide immunity 3 . Some human immune genes are homologous with antiphage defense genes in bacteria, though the extent of this overlap is not known 4–12 . Here, we screened a panel of human innate immune genes for phage defense in Escherichia coli and found...

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Literature Corpus work: 5dd66003-ab43-538d-bb47-7d01643ac7a9
DOI: 10.64898/2026.06.30.735675

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